منابع مشابه
Translating the A1C Assay
In the clinical management of diabetes, the A1C assay has become indispensable. Used worldwide to monitor chronic glycemia, the assay is an essential tool to determine whether a patient has achieved the core goal of therapy for diabetes: a marked and sustained reduction in plasma glucose to achieve as close to a normal level as can be safely attained. With the publication of the A1c-Derived Ave...
متن کاملTranslating the A1C Assay Into Estimated Average Glucose Values
OBJECTIVE The A1C assay, expressed as the percent of hemoglobin that is glycated, measures chronic glycemia and is widely used to judge the adequacy of diabetes treatment and adjust therapy. Day-to-day management is guided by self-monitoring of capillary glucose concentrations (milligrams per deciliter or millimoles per liter). We sought to define the mathematical relationship between A1C and a...
متن کاملTranslating “Nondiabetic” A1C Levels to Clinical Practice
It is well recognized that there is a significant delay from the time clinical research findings are first reported and when the results become an integral part of clinical care. With the understanding that the prevalence and incidence of diabetes is increasing worldwide, and that the resulting complications are a major contributor to morbidity and mortality, the need for more rapid clinical tr...
متن کاملTranslating Hemoglobin A1c Scores across an Ethnically Diverse Population: Is the Language Consistent across All Races?
Hemoglobin A1c testing is an accepted measure of how well the blood glucose level has been controlled in the recent past (six to eight weeks) among individuals with diabetes. The purpose of this study was to evaluate the relationship between hemoglobin A1c (HbA1c) and blood glucose in an ethnically diverse population in a clinical setting. A cross-sectional research design was employed to explo...
متن کاملAn automated "high-pressure" liquid-chromatographic assay for hemoglobin A1c.
An automated "high-pressure" liquid-chromatographic assay for hemoglobin A1c is described. We use a 45-min incubation in acetate buffer (pH 5.5) to eliminate labile glycated hemoglobins. In this automated system conventional modules are used but it incorporates a solvent-switching valve to select either of two buffers, which differ in pH and NaCl concentration. The chromatographic column contai...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2008
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc08-0878